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[DOI] [PubMed] [Google Scholar] Liu L.X., Zhang Y.Y., Liu T., Ke C.R., Huang J.Z., Fu Y.J., et al

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[13] [15] Post-marketing use of azelaic acid has been associated with the development of hypersensitivity reactions (including angioedema, ocular inflammation, facial swelling, and urticaria) and asthma exacerbation (i.e., dyspnea, wheezing)

These pathways are evaluated within controlled laboratory systems to support investigation of enzyme-mediated methylation processes, nicotinamide metabolism, and related intracellular signaling dynamics