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The weight loss observed was 4.5%, 9.2%, and 10.6% higher than the placebo for the 0.25 mg, 0.5 mg, and 1.0 mg doses of Tesofensine, respectively

Although extremely costly and time-consuming, these outcome trials have, nevertheless, provided us with extremely valuable information about the natural history of the diseases, drug safety and the influence of the drugs on the disease progression