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Litchfield, Melrose Consultancy, Denmans Lane, Fontwell, Arundel, West Sussex, United Kingdom (CAG Joint Rapporteur) Professor M

Peer review This article was medically reviewed by Chelsie Rogers, PA-C, a board-certified physician assistant with 6 years of experience in cosmetic dermatology

The first showed that SF treatment (56.4 mol/kg/day for 10 days) upregulated Nrf2 and BDNF while downregulating MeCP2 in SH-SY5Y cells (84)

Pharmacokinetic parameters such as AUC, maximum plasma concentration (Cmax), terminal elimination t1/2, volume of distribution (Va), and clearance were calculated [2]