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In preclinical studies, it inhibited proliferation of a broad range of tumor cell lines (cell IC50 6.2 nM to 4.3 M) and inhibited HUVEC growth in response to HGF and VEGF as an in vitro model of angiogenesis [116]

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Disclosure of interest: No 1 - ICH & SAH 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.03 - EPIDEMIOLOGY & RISK FACTORS P141 - ESOC25-1813 ASSOCIATIONS OF CHRONIC KIDNEY DISEASE WITH RECURRENT STROKE EVENTS IN PATIENTS WITH ACUTE INTRACEREBRAL HAEMORRHAGE Philip Nash 1,2 , Simon Fandler-Hfler, Gareth Ambler 3 , Lena Obergottsberger 4 , Larysa Panteleienko 1 , Rom Mendel 1 , Wenpeng Zhang 1 , Hatice Ozkan 1,2 , Gerit Wnsch 5 , Rolf Jger 6 , Christian Enzinger, David C