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We wondered whether inhibition of TS in cells surviving 5FU treatment promoted the observed reprogramming of mitochondria towards increased biogenesis and activity

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The procedure was repeated for total enzymatic rates of product formed using reaction mixtures containing, in addition, aliquots (5 l) of glutathione transferase solution (protein concentration 810 g/ml)

Briefly, GPx intervention studies through genetic manipulation or selenium supplementation or synthetic mimic have conveyed contradictory viewpoints, with some reports showing a positive role of seleno-GPxs in offering radioresistance, while others reject such claims