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The effect of NAC versus placebo will be explored in subgroups of interest with results tabulated (estimated hazard ratio by subgroup, corresponding 95% confidence interval and p-value) as well as displayed via forest plots

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Indeed, previous work revealed that epithelial stem cells of the skin are able to acquire wound memory also distally from the lesion site, that predisposes to skin cancer [161]

Although onion has mild but not significant effects on hepatic ALP activity, it has a significant effect on alkaline phosphatase (ALP) in the Cd -exposed rats