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Children with severe deficiency can suffer from rickets, characterised by soft and weak bones

First, routine screening for vitamin B12 deficiency should be incorporated into primary care for high-risk populations such as older adults, women of reproductive age, vegetarians, and patients with diabetes or chronic use of metformin or proton pump inhibitors

Keep vials in their original packaging to protect them from light, which can also cause degradation over time

Remarkably, Erastin highly increased OCR in LDHB KD (siLDHB + Erastin) but not in control A549 cells (siNT + Erastin) ( Figure 4d, Supplementary Figure 8c ), suggesting that cancer cells subjected to combined inhibition of LDHB and SLC7A11 undergo a high level of OXPHOS