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Pre-injury supplementation with Immunocal preserves brain GSH/GSSG ratio and ameliorates biochemical and histopathological indices of oxidative damage and neuronal injury induced by a moderate TBI Several biochemical and histopathological indices of neuronal injury were evaluated in mice subjected to TBI

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(2) DHODH: DHODH is a mitochondrial flavoprotein localized to the inner mitochondrial membrane, where it catalyzes the fourth and rate-limiting step of de novo pyrimidine biosynthesisthe oxidation of dihydroorotate to orotate 42,43