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Accordingly, PPARA and its target gene, CPT1A , were significantly downregulated in both primary hepatocytes (Extended Data Fig

was financed by grants from the Swedish state under the agreement between the Swedish government and the county councils, the ALF-agreement (grant numbers ALFGBG-1005471, ALFGBG-965923, ALFGBG-81392, ALFGBG-771071), the Alzheimerfonden (grant numbers AF-842471, AF-737641, AF-929959, AF-939825), the Swedish Research Council (grant numbers 2019-02075, 2019-02075_15), Stiftelsen Psykiatriska Forskningsfonden and The Swedish Brain Foundation FO2024-0097