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The induction of a ferroptosis vulnerable state with PUFA accumulation/lipid peroxidation was more evident after 5-14 days of treatment, correlating with the time required to establish a quiescent/senescent phenotype 53,54

Since vitamin B12 supports red blood cell production (via ODS), it is conceivable that when a vitamin B12 deficiency is treated with high dosage supplementation, the result may be the overproduction of red blood cells

Dietary LC increased the ATP dynamic process and mitochondrial number, decreased mitochondrial DNA damage and enhanced the protein expression of mitochondrial -oxidation, biogenesis and mitophagy

Detoxification is primarily managed by the liver and kidneys, which filter and eliminate waste and toxins from the body