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World J Gastroenterol 23(47):82638276

the biosynthesis of secondary metabolites is usually induced by various ecological stress, pathogen attacks, and nutritional deficiencies 6 , which in this case usually produce excess ROS

, Some of the genes that regulate and are regulated by Pax6 at early stages of eye formation are now known, although the number of genes involved and knowledge about their interactions is likely to increase

In a plateau environment, due to the enhanced vasoconstrictive response under hypoxic conditions, plateau residents are more likely to develop hypoxia-related adaptive changes, thereby affecting their mean pulmonary artery pressure levels