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Although there is little evidence of Parkin-independent mitophagy being involved in PD, these alternative mitophagy mechanism, such as MUL1- or NIX-involved mitophagy as discussed above, may be utilized to correct the mitophagy defects to rescue neurodegeneration in PD

Patients who have had allergic reaction to vitC or glutathione, history of keloid, concurrent skin infection on face, previous used of any medication or laser that have whitening effect (hydroquinone, arbutin, azelaic acid, kojic acid, licorice extract, Lakoocha extract, vitC, vitamin E, soybean extract, resorcinol, alpha/beta-hydroxy acid, nicotinamide) for 1 week before enrolled, were excluded

We observed a two-way ANOVA interaction effect on Txnrd2 gene expression

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