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Studies have shown that cats with IBD, intestinal lymphoma, and pancreatitis tend to have much lower levels of B12 in their bodies than healthy cats

Specifically, grade 0 indicates normal lung, grades 12 indicate minimal to moderate fibrous thickening of alveolar or bronchiolar walls without significant architectural damage, grades 34 indicate moderate thickening with some damage to lung structure and formation of fibrous bands, grades 56 indicate severe fibrosis with definite distortion of architecture and large fibrous areas, and grades 78 indicate very severe fibrosis with near-total or total fibrous obliteration of the field

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The body can excrete excess vitamin B12, and many people with a deficiency or increased need actually benefit from moderate to higher doses