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Has the applicant demonstrated that the following statement in their proposed modified risk labeling and advertising is true: Scientific studies have shown that switching completely from cigarettes to the IQOS system significantly reduces your bodys exposure to harmful or potentially harmful chemicals.

Don follows up with a speech saying that people want reassurance that what they are doing is ok

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We found that CM from nicotine-induced N2-neutrophils strongly promoted MET phenotype in both cancer cells (Fig