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The mainstay of therapy is intensive behavioral interventiongiven for 20 or more hours per weekwhich has been shown to produce important benefits, but response to treatment varies widely, and it is challenging to predict which children will respond [5]

[DOI] [PMC free article] [PubMed] [Google Scholar] Lee A.H., Scapa E.F., Cohen D.E., Glimcher L.H

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PP2A can be deactivated by ROS which may in turn inhibit Akt/PKB