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When the GSH concentration in the dialysis medium was 2 M, the cumulative release of GNA after 72 h increased to 18.6%, indicating that the disulfide bonds remained largely intact at low reductant concentrations, allowing for effective drug retention during blood circulation

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However, some studies claim that vitamin E supplementation does not reduce the risk of AD and slows down its pathogenesis (Dysken et al., 2014

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