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Research across different models has been instrumental in elucidating a wide array of therapeutic mechanisms

In the case of Alzheimers and Parkinsons diseases, and likely in other conditions marked by energetic insufficiency, iron accumulation may paradoxically coexist with a functional iron deficiency, starving the mitochondria

Instead, a large number of genes encoding class III peroxidases are rapidly and greatly upregulated and peroxidase activity increases in apoplastic space 28