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Later, it was also reported that curculigoside can inhibit osteoclast genesis by reducing ROS generation by means of decreasing the activity of oxidase while activating the NrF2 pathway and suppressing the NF- kB signaling pathway in RAW264.7 cells [96]

VIC leads to the inhibition of cell proliferation and growth by generating ROS and altering the expression of genes involved in angiogenesis, glycolysis, and metastasis by regulating the transcriptional activity of hypoxia

J Cell Mol Med 24(22):13163-13170, 2020

BAM15 Another mitochondrial uncoupler that enhances fat oxidation and improves metabolic flexibility while addressing the root causes of low energy