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126, 706715.10.1104/pp.126.4.1706 11 FrendoP.MathieuC.Van de SypeG.HrouartD.PuppoA

New techniques, such as NMR-based fragment screening, tethering, and in silico drug design, have been used to discover novel agents that bind directly to KRAS, although there is a long way off to achieve targeted KRAS