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Rev-erb- modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Abdelall W, Kantarjian HM, Borthakur G , Garcia-Manero G, Patel KP, Jabbour EJ, Daver NG, Kadia T, Gborogen RA, Konopleva M, Ravandi F, Andreeff M, Cortes JE

Deep sleep is the restorative phase of sleep where the body undergoes essential processes such as tissue repair, muscle growth, and hormone regulation

The wide variation in extracellular (e.g., 220 mol/L in plasma) and intracellular (0.510 mM) GSH concentrations in animal cells [15] led to the notion that this leads to a large difference in reducing potential between the intracellular and extracellular compartments that could be exploited for triggered intracellular delivery of several bioactive molecules [77]