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This syndrome demonstrates a cytokine elevation profile that closely resembles that seen in HLH, with IL-6, IFN-, and IL-1 playing key roles (Fig

The Society recognizes that it must assume, also, a role of advocacy for those who are defenseless or voiceless

The loss of a single allele of AMPK- increases the development of B-cell lymphoma in mice with c-Myc transgenic expression in B-cells, whereas the loss of both alleles prompts a severe outcome (156)