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Detoxification and Antioxidant Support NAC plays a direct role in detoxifying harmful substances in the body

"This is important because it can affect how well the anesthesia works

Note that dolutegravir-lamivudine should not be used as initial therapy in the following three situations: (1) the baseline HIV RNA level is greater than 500,000 copies/mL, (2) the person undergoing treatment has chronic hepatitis B virus (HBV) or the HBV status is unknown, or (3) results from HIV genotypic resistance testing or hepatitis B serology are not available at the time antiretroviral therapy is planned to start.[69] The other recommended regimens can be initiated prior to the availability of genotype resistance test results