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An experimental study showed that Beclin-1 and LC3 levels were increased, whereas Bcl-2 level was reduced within 48 h following seizure in rats (Li et al

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The triggered signaling process leads to the expression of proinflammatory cytokine-inducing transcription factors, such as NF-kB, as well as to activate interferon regulatory factors that mediate the type I interferon-dependent antiviral response [17]

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The difference can be as large as 0.025 g/kg in the open ocean (Figure 1b)

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