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Vitamin B12 Regulates Cytokines and Neurotrophic Factors A very new research field has brought to light astonishing new functions of B12 in the nervous system, which go far beyond its role as coenzyme and rather resemble the mode of action of a hormone: vitamin B12 regulates the level of certain neurotrophic factors such as neurotransmitters, growth factors and the so-called cytokines essential messenger substances that all assume a controlling function in numerous bodily processes (32)

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The peptide is establishing tissue saturation

Current practice patterns extrapolated from animal studies and online communities typically involve subcutaneous injection of 0.25-0.5 mg once or twice daily, or oral administration of 0.5-1 mg daily to compensate for lower bioavailability