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Embodiment 218 The method according to any one of embodiments 216- 217, wherein the persisting population of genetically engineered T cells persists in the human for at least three months, or for at least four months, or for at least five months, or for at least six months, or for at least seven months, or for at least eight months, or for at least nine months, or for at least ten months, or for at least eleven months, or for at least twelve months, or for at least two years, or for at least three years after administration

380 Overall, these results suggest that the symptoms of UC could be alleviated by regulating the formation and activation of inflammasomes and reducing the release of inflammatory mediators

The most common adverse events are gastrointestinal in nature, including nausea (20-47% depending on dose), constipation (21%), fatigue (20%), and vomiting (8%)

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