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Patients with active cancer, a history of pituitary tumors, or severe metabolic disease should discuss growth-hormone peptide therapy carefully with both their primary clinician and specialist before starting

J Neuropathol Exp Neurol 59:314322

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Interspecies scaling (for example, body-surface-area conversion) typically reduces a rodent mg/kg figure severalfold, and even a properly scaled number would still be a hypothetical exposure , not a validated dose