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7 Therapeutic strategies and clinical translation With the deepening understanding of ferroptosis mechanisms, an increasing number of molecular targets have been identified as closely associated with the pathological progression of AD

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Nonpharmacologic treatment options with published evidence of efficacy in patients with CIPN include chemotherapy dose reduction, discontinuation of the offending chemotherapeutic agent(s), acupuncture, avoiding cold temperatures/maintaining warmth, physical activity, and massaging affected areas ( TABLE 3 )