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After 30 days on the 1.5 mg dose, increase the dose to 4 mg once daily

Participants will learn how to assess B12 deficiency symptoms, determine appropriate dosages, and perform intramuscular or subcutaneous injections safely and effectively

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The differences in performance of Co 2+ - and Ni 2+ -based IMAC resins is a result of the spatial positioning of each metal ion in the reactive core influencing the specificity and capacity of histidine binding (because, as all protein researchers know, structure impacts function!) Cobalt-based resins offer better specificity, resulting in higher purity, while nickel-based resins offer better adsorption, resulting in higher binding capacity