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These compounds can neutralize free radicals and reduce oxidative stress, mechanisms implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimers disease and Parkinsons disease (404, 405)

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The elabela-APJ axis could mitigate neuronal ferroptosis following ischemic stroke, and the ELA-32 peptide may be a potential therapeutic candidate for ischemic stroke and cardiovascular diseases