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Addressing these challenges will identify selective cellular and molecular pathways linking ceramides metabolism to neurodegenerative disorders, which are essential for translating IF into sustainable and broadly applicable strategies in clinic for improving brain health potentially focusing on neurodegeneration

NETs induce CXCL1, CXCL2, and CXCL8 expression in airway cells through TLR4/NF-B signaling, thereby recruiting neutrophils to inflammatory sites

Specifically, treatment with erastin, a known FIA, significantly increased the expression of CHAC1 mRNA compared to non-treated control islets

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