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10.1016/j.ijsu.2015.03.023 14

Nonenzymatic cleavage of proteins by reactive oxygen species generated by dithiothreitol and iron

The first line of defense is SOD, which reduces hydroxyl radicals and removes superoxide radicals by turning them into oxygen and hydrogen peroxide

H-ferritin nanoparticles have emerged as a therapeutic nanoplatform for inflammation-related AD, exhibiting favorable properties that enhance curcumin encapsulation and neuroprotective effects by reducing microgliosis and astrogliosis, while also improving cognitive performance in 5xFAD mice (Morasso et al., 2024)