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However, the decrease in serum levels of FBG was more pronounced in vitamin B12 than in the placebo group

Twenty-nine participants with erosive OLP accompanied by stage IIIV periodontitis will be recruited from the Department of Oral Mucosal Diseases at the Ninth Peoples Hospital affiliated to Shanghai Jiao Tong University School of Medicine (main center), Department of Stomatology at Shanghai Baoshan Hospital (sub-center I), Periodontal Disease Department of the First Affiliated Hospital of Xinjiang Medical University (sub-center II), Stomatology Hospital affiliated to Zhejiang University School of Medicine (sub-center III), and Department of Stomatology at Huashan Hospital (sub-center IV)

[3] The proposed mechanism involves B12 altering the gene expression of skin bacteria ( Cutibacterium acnes ), leading to increased inflammatory compounds