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Alterations in regulators of the renal-bone axis, inflammation and iron status in older people with early renal impairment and the effect of vitamin D supplementation

Chronic infection and inflammation can deplete endogenous antioxidants such as glutathione, catalase, and vitamins C and E, resulting in amplification for the oxidative stress and cellular damage, and this may have negative effect by causing damage to the alveolar-capillary membrane which causes increased permeability, pulmonary edema, decreased gas exchange, and prolonged oxidative stress causing inflammation, fibrosis, and long-term lung damage

To view a copy of this license, visit About this article Cite this article Dou, X., Li, S., Hu, L

On the other hand, ferroptosis, a unique form of non-apoptotic cell death, can be initiated by the accumulation of iron and production of reactive oxygen species (ROS) from lipid peroxidation [31]