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Insights into the conversion of SetCys to a Cys residue From a mechanistic point of view, the loss of the selenoethyl group from the SetCys residue seems unlikely to involve radical intermediates since the reaction proceeds well in the presence of a large excess of sodium ascorbate and MPAA 27,28 , two reagents known to be powerful quenchers of alkylselenyl or alkylthiyl radicals

Others start with KLOW and transition to GLOW once inflammatory conditions are controlled