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The IUCN Red List classification is a fundamental framework for conservation and biodiversity research, e.g., informing policy decisions and contributing key indicators to the Kunming-Montreal Global Biodiversity Framework ( and the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) reporting 1

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Evidence suggests that: combination NRT (a patch combined with a fast-acting product) or varenicline are equally effective as quitting aids [footnote 42] all of the licensed forms of NRT (gum, transdermal patch, nasal spray, inhalator and sublingual tablets or lozenges) can help people who make a quit attempt to increase their chances of successfully stopping smoking

The formation of significant amounts of 1a-d is consistent with the chemical literature