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An added concern is that the few products showing some efficacy, such as varenicline (Chantix) and combination nicotine replacement therapies, involve high costs that many smokers are reluctant or unable to afford

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The mechanism of the toxicity in macadamia nuts is unknown, but a toxic dose is no more than 5 grams per 1 lb of a dogs body weight

Insights into the smoking epidemic across cohorts Our cohort-by-age analysis of high-income regions confirmed the mortality element of the smoking epidemic model [4, 5]: the increase in smoking-attributable mortality started later among females than for males, and resulted in a later peak at a lower level