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Mitochondrial apoptosis also plays an indispensable role in this, and Omega-3 fatty acids can inhibit the mitochondrial apoptosis pathway, DHA upregulates the anti-apoptotic protein Bcl-2, inhibits the translocation of the pro-apoptotic protein Bax to mitochondria, and prevents the release of cytochrome C (89, 90)

confirmed that in MII mouse oocytes, oxidative stress-catalyzed lipid peroxidation could initiate cyclic ROS transmission by directly destroying mitochondrial components (Lord et al., 2015)

Defining a critical period in calvarial development for Hedgehog pathway antagonist-induced frontal bone dysplasia in mice

Since their first report in 1990, SELEX technology has been continuously improved, 174,175 diversifying the selection and development of high-affinity aptamers