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We identified programmed cell death protein 5 (PDCD5) as a target gene of Lgr5 and we found that PDCD5 was responsible for Lgr5-mediated Dox resistance

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The p values were adjusted using the Benjamini and Hochberg method

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The qRT-PCR was carried out in the CFX96 Touch Real-Time PCR detection system (Bio-Rad, Hercules, CA, USA)

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