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Aeroallergens induce reactive oxygen species production and DNA damage and dampen antioxidant responses in bronchial epithelial cells

It came from the Andes, supposedly the result of the natural cross breeding of two wild species producing the rustica tobacco, which then likely became a domesticated crop in this region

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In contrast, in DSS-induced UC-like colitis, cigarette smoke exposure similarly increases GPR15 expression on T cells but promotes their differentiation into Treg cells, conferring a protective effect against disease progression (Fig