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This late-onset disease is characterized by selective loss of upper and lower motor neurons in the cerebral cortex, brainstem and spinal cord, causing progressive muscle weakness, atrophy and paralysis, leading to death due to respiratory failure[1, 2, 5]

2023YFC3404700), the National Natural Science Foundation of China (No

Dupixent pipelines NO.4 Eliquis Company: BMS/Pfizer 2024 worldwide sales forecast: $13.31 billion Eliquis (apixaban) is an orally administered selective factor Xa inhibitor jointly developed by BMS and Pfizer, starting in 2007