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if left unchecked, it can rise to very high levels

Personally, and this is the next phase of our research, I believe that oxidative stress and neuroinflammation, and possibly a secondary mitochondrial dysfunction, may all be co-conspirators in the etiology of most of these unexplained and highly overlapping and related multisystem/multisymptom diseases like ME/CFS, FM, Gulf War, IBS, etc

doi:10.1038/jid.2012.260

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