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In people with slower ALDH activity, acetaldehyde accumulates, prolonging oxidative stress and amplifying the inflammatory response

Peptides are short chains of amino acids that act as messengers in the body, helping cells communicate more effectively and encouraging optimal function at a cellular level

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Mtb aggregates can feed on the dead macrophages in an ESX-1 and bacterial lipid phthiocerol dimycocerosate (PDIM) dependent manner, without the need for live AMs, thereby avoiding phagocytosis (84).They can further kill other macrophages resulting in a cascade of cell death and inflammation, boosting Mtb transmission