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Tocris, #1254) was added for the first 23 days

Research (primarily in animal models) has shown potential effects such as: Supporting soft tissue repair (muscle, tendon, ligament) Promoting angiogenesis (formation of new blood vessels) Supporting gastrointestinal integrity and mucosal protection Modulating inflammatory responses While these findings are promising, clinical research in humans remains limited, and results should be interpreted with caution

Physostigmine is not recommended, except for the treatment of life-threatening symptoms and are unresponsive to other methods of treatment, and only with inpatient treatment

These subgroup analyses are shown in Table 12 and Figures 3 and 4