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Low levels of glutathione and often concurrently high levels of inflammation are found in many chronic disease states

Results The cohort characteristics Table 1 summarizes cohort characteristics of healthy controls and patients with FCMD

Similarly, another study demonstrated nephrotoxicity in colitis mice treated with green tea extract containing 35% EGCG, evidenced by increased serum creatinine levels (a nephropathy biomarker), and elevated expression of antioxidant enzymes (HO-1 and NQO1) and HSP 90 (238)

These findings suggest that SPAE mitigates DEX-induced hepatic stress by modulating upstream regulators of antioxidant and metabolic pathways, namely, Keap1 and AMPK, as shown in Figure 8