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Ageing Res Rev 67:101271

Moreover, the simulation trajectories were visualized and captured by VMD 1.9.2 software 52

Mitochondrial NAD+/NADH ratios stay at 7-8, which is much lower than cytoplasmic ratios that range from 60-700 [11]

(2022) have explored that the -elemene integrated with erlotinib enhanced the cytotoxicity of erlotinib against EGFR mutated primary EGFR-TKI resistant NSCLC cells, and diminished the content of ferroptosis negative regulatory proteins (glutaminase, FTH1, Nrf2, Slc7a11 and GPX4), added ROS and lipid peroxidation levels, and accomplished anti-tumor effects through ferroptosis