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These symptoms vary in severity and include irritability, anxiety, depressed mood, difficulty concentrating, increased appetite, and sleep disturbances

Desert Indians regarded smoking as a cure for colds, especially if the tobacco was mixed with the leaves of the small Desert sage, Salvia dorrii , or the root of Indian balsam or cough root, Leptotaenia multifida , the addition of which was thought to be particularly good for asthma and tuberculosis

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