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Acylcarnitine also helps promote intestinal peristalsis, which has been shown to be significantly positively correlated with the defecation frequency and can relieve constipation symptoms [236]

Brown is with the Nutritional Medicine Institute, London, UK, and the British College of Nutrition and Health (BCNH), London, UK

Interestingly, NOX1-null mice are protected from diabetic endothelial dysfunction, and mice lacking components of NOX2 are protected against hypertension and show reduced atherosclerotic lesion formation when crossed with the apoE-/- background (Judkins et al., Figure 1 ROS derived from mitochondria induce the infiltration and activation of inflammatory cells and increase the apoptosis of endothelial and vascular smooth muscle cells (Hulsmans et al., 2010)

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