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AQP4 is involved in cell volume control and K + homeostasis (through interaction with other membrane proteins 575,576 ) and appears to be pro-inflammatory in different experimental models of neurological disease 577,578

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Lipid Metabolism & 3-AR Mechanism Heffernan et al., Endocrinology (2001) Heffernan and colleagues investigated the lipolytic effects of chronic AOD-9604 treatment using two complementary mouse models: diet-induced obese C57BL/6J mice and beta3 adrenergic receptor (3-AR) knockout mice