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doi: 10.1038/s41467-020-17402-2 164 BoitsovaEBMorgunAVOsipovaEDPozhilenkovaEAMartinovaGPFrolovaOVet al

Disease claims on the label or listing: Any supplement claiming to cure, treat, or prevent a disease is violating FSSAI and ASCI regulations

Esaki 2005)

Evidence suggests that GPR81 is an anti-inflammatory pathway that inhibits NLRP3 inflammasome release by activating the intracellular adaptor protein, -arrestin 2 (ARRB2), and attenuating NF-B activity ( Figure 3 ) (159)