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There was no significant clinical evidence to prove that Vitamin C injection either in single doses or in combination with glutathione and collagen can improve skin elasticity and whiten the skin

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Strength points and limitations Based on our knowledge, this is the most updated meta-analysis on this topic, including all available evidence based on our inclusion criteria of including only controlled studies, either RCTs or controlled observational studies, to reach the highest accessible quality of evidence from the available evidence found in the literature